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Regulating T Cell Population Alleviates SLE by Inhibiting mTORC1/C2 in MRL/lpr Mice

It’s well known that the mammalian target of rapamycin (mTOR) exerts a critical role in the regulator of immune cells and is associated with T cells dysfunction in patients with systemic lupus erythematosus (SLE). Antigen-induced T-cell proliferation via mTORC1 suppressed by Rapamycin has been used...

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Detalles Bibliográficos
Autores principales: Zhang, Dongya, Wang, Meiling, Shi, Guoping, Pan, Peng, Ji, Jianjian, Li, Pengfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883674/
https://www.ncbi.nlm.nih.gov/pubmed/33597869
http://dx.doi.org/10.3389/fphar.2020.579298