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Gene dysregulation analysis builds a mechanistic signature for prognosis and therapeutic benefit in colorectal cancer

The implementation of cancer precision medicine requires biomarkers or signatures for predicting prognosis and therapeutic benefits. Most of current efforts in this field are paying much more attention to predictive accuracy than to molecular mechanistic interpretability. Mechanism-driven strategy h...

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Detalles Bibliográficos
Autores principales: Li, Quanxue, Dai, Wentao, Liu, Jixiang, Sang, Qingqing, Li, Yi-Xue, Li, Yuan-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883816/
https://www.ncbi.nlm.nih.gov/pubmed/32717065
http://dx.doi.org/10.1093/jmcb/mjaa041