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Toward precise CRISPR DNA fragment editing and predictable 3D genome engineering

Ever since gene targeting or specific modification of genome sequences in mice was achieved in the early 1980s, the reverse genetic approach of precise editing of any genomic locus has greatly accelerated biomedical research and biotechnology development. In particular, the recent development of the...

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Detalles Bibliográficos
Autores principales: Wu, Qiang, Shou, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883824/
https://www.ncbi.nlm.nih.gov/pubmed/33125070
http://dx.doi.org/10.1093/jmcb/mjaa060