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Active hematopoiesis triggers exosomal release of PRDX2 that promotes osteoclast formation

Hematopoietic disorders, particularly hemolytic anemias, commonly lead to bone loss. We have previously reported that actively proliferating cancer cells stimulate osteoclastogenesis from late precursors in a RANKL‐independent manner. We theorized that cancer cells exploit the physiological role of...

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Detalles Bibliográficos
Autores principales: Sadvakassova, Gulzhakhan, Tiedemann, Kerstin, Steer, Kieran J. D., Mikolajewicz, Nicholas, Stavnichuk, Mariya, In‐Kyung Lee, Irene, Sabirova, Zarina, Schranzhofer, Matthias, Komarova, Svetlana V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883842/
https://www.ncbi.nlm.nih.gov/pubmed/33587325
http://dx.doi.org/10.14814/phy2.14745