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Active hematopoiesis triggers exosomal release of PRDX2 that promotes osteoclast formation
Hematopoietic disorders, particularly hemolytic anemias, commonly lead to bone loss. We have previously reported that actively proliferating cancer cells stimulate osteoclastogenesis from late precursors in a RANKL‐independent manner. We theorized that cancer cells exploit the physiological role of...
Autores principales: | Sadvakassova, Gulzhakhan, Tiedemann, Kerstin, Steer, Kieran J. D., Mikolajewicz, Nicholas, Stavnichuk, Mariya, In‐Kyung Lee, Irene, Sabirova, Zarina, Schranzhofer, Matthias, Komarova, Svetlana V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883842/ https://www.ncbi.nlm.nih.gov/pubmed/33587325 http://dx.doi.org/10.14814/phy2.14745 |
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