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Adrenal gland as a sanctuary site for immunotherapy in patients with microsatellite instability-high metastatic colorectal cancer

Metastatic colorectal cancers (mCRC) harboring microsatellite instability (MSI) are sensitive to immune checkpoint inhibitors (ICIs), but the mechanisms of resistance to ICIs remain unclear. Dissociated responses in patients with ICI-treated cancer suggest that certain organs may serve as sanctuary...

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Detalles Bibliográficos
Autores principales: Cohen, Romain, Jonchère, Vincent, De La Fouchardière, Christelle, Ratovomanana, Toky, Letourneur, Quentin, Ayadi, Mira, Armenoult, Lucile, Buisson, Adrien, Sarabi, Matthieu, Pellat, Anna, Colle, Raphael, Paye, Francois, Meeus, Pierre, Svrcek, Magali, Duval, Alex, Andre, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883858/
https://www.ncbi.nlm.nih.gov/pubmed/33579738
http://dx.doi.org/10.1136/jitc-2020-001903