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Adrenal gland as a sanctuary site for immunotherapy in patients with microsatellite instability-high metastatic colorectal cancer
Metastatic colorectal cancers (mCRC) harboring microsatellite instability (MSI) are sensitive to immune checkpoint inhibitors (ICIs), but the mechanisms of resistance to ICIs remain unclear. Dissociated responses in patients with ICI-treated cancer suggest that certain organs may serve as sanctuary...
Autores principales: | Cohen, Romain, Jonchère, Vincent, De La Fouchardière, Christelle, Ratovomanana, Toky, Letourneur, Quentin, Ayadi, Mira, Armenoult, Lucile, Buisson, Adrien, Sarabi, Matthieu, Pellat, Anna, Colle, Raphael, Paye, Francois, Meeus, Pierre, Svrcek, Magali, Duval, Alex, Andre, Thierry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883858/ https://www.ncbi.nlm.nih.gov/pubmed/33579738 http://dx.doi.org/10.1136/jitc-2020-001903 |
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