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Open Search Strategy for Inferring the Masses of Cross-Link Adducts on Proteins

[Image: see text] Development of new reagents for protein cross-linking is constantly ongoing. The chemical formulas for the linker adducts formed by these reagents are usually deduced from expert knowledge and then validated by mass spectrometry. Clearly, it would be more rigorous to infer the chem...

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Detalles Bibliográficos
Autores principales: Slavin, Moriya, Tayri-Wilk, Tamar, Milhem, Hala, Kalisman, Nir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883999/
https://www.ncbi.nlm.nih.gov/pubmed/33237725
http://dx.doi.org/10.1021/acs.analchem.0c03292