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Protein signatures of centenarians and their offspring suggest centenarians age slower than other humans

Using samples from the New England Centenarian Study (NECS), we sought to characterize the serum proteome of 77 centenarians, 82 centenarians' offspring, and 65 age‐matched controls of the offspring (mean ages: 105, 80, and 79 years). We identified 1312 proteins that significantly differ betwee...

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Detalles Bibliográficos
Autores principales: Sebastiani, Paola, Federico, Anthony, Morris, Melody, Gurinovich, Anastasia, Tanaka, Toshiko, Chandler, Kevin B., Andersen, Stacy L., Denis, Gerald, Costello, Catherine E., Ferrucci, Luigi, Jennings, Lori, Glass, David J., Monti, Stefano, Perls, Thomas T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884029/
https://www.ncbi.nlm.nih.gov/pubmed/33512769
http://dx.doi.org/10.1111/acel.13290