Decreased p53 is associated with a decline in asymmetric stem cell self‐renewal in aged human epidermis

With age, the epidermis becomes hypoplastic and hypoproliferative. Hypoproliferation due to aging has been associated with decreased stem cell (SC) self‐renewal in multiple murine tissues. The fate of SC self‐renewal divisions can be asymmetric (one SC, one committed progenitor) or symmetric (two SC...

Descripción completa

Detalles Bibliográficos
Autores principales: Charruyer, Alexandra, Weisenberger, Tracy, Li, Hang, Khalifa, Ayman, Schroeder, Andrew W., Belzer, Annika, Ghadially, Ruby
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884041/
https://www.ncbi.nlm.nih.gov/pubmed/33524216
http://dx.doi.org/10.1111/acel.13310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884041/
https://www.ncbi.nlm.nih.gov/pubmed/33524216
http://dx.doi.org/10.1111/acel.13310

Ejemplares similares