JUNB‐FBXO21‐ERK axis promotes cartilage degeneration in osteoarthritis by inhibiting autophagy

Osteoarthritis (OA) is a heterogeneous disease that is extremely hard to cure owing to its complex regulation network of pathogenesis, especially cartilage degeneration. FBXO21 is a subunit of ubiquitin E3 ligases that degrades P‐glycoprotein and EID1 by ubiquitination and activates the JNK and p38...

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Detalles Bibliográficos
Autores principales: Lin, Zhiming, Miao, Jianing, Zhang, Tao, He, Ming, Wang, Ziyuan, Feng, Xinyuan, Bai, Lunhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884044/
https://www.ncbi.nlm.nih.gov/pubmed/33450132
http://dx.doi.org/10.1111/acel.13306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884044/
https://www.ncbi.nlm.nih.gov/pubmed/33450132
http://dx.doi.org/10.1111/acel.13306

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