Metformin treatment in late middle age improves cognitive function with alleviation of microglial activation and enhancement of autophagy in the hippocampus

Metformin, a drug widely used for treating diabetes, can prolong the lifespan in several species. Metformin also has the promise to slow down age‐related cognitive impairment. However, metformin's therapeutic use as an anti‐aging drug is yet to be accepted because of conflicting animal and huma...

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Detalles Bibliográficos
Autores principales: Kodali, Maheedhar, Attaluri, Sahithi, Madhu, Leelavathi N., Shuai, Bing, Upadhya, Raghavendra, Gonzalez, Jenny Jaimes, Rao, Xiaolan, Shetty, Ashok K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884047/
https://www.ncbi.nlm.nih.gov/pubmed/33443781
http://dx.doi.org/10.1111/acel.13277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884047/
https://www.ncbi.nlm.nih.gov/pubmed/33443781
http://dx.doi.org/10.1111/acel.13277

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