GWAS of three molecular traits highlights core genes and pathways alongside a highly polygenic background

Genome-wide association studies (GWAS) have been used to study the genetic basis of a wide variety of complex diseases and other traits. We describe UK Biobank GWAS results for three molecular traits—urate, IGF-1, and testosterone—with better-understood biology than most other complex traits. We fin...

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Detalles Bibliográficos
Autores principales: Sinnott-Armstrong, Nasa, Naqvi, Sahin, Rivas, Manuel, Pritchard, Jonathan K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884075/
https://www.ncbi.nlm.nih.gov/pubmed/33587031
http://dx.doi.org/10.7554/eLife.58615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884075/
https://www.ncbi.nlm.nih.gov/pubmed/33587031
http://dx.doi.org/10.7554/eLife.58615

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