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Calcium Dobesilate (CaD) Attenuates High Glucose and High Lipid-Induced Impairment of Sarcoplasmic Reticulum Calcium Handling in Cardiomyocytes

Calcium dobesilate (CaD) is used effectively in patients with diabetic microvascular disorder, retinopathy, and nephropathy. Here we sought to determine whether it has an effect on cardiomyocytes calcium mishandling that is characteristic of diabetic cardiomyopathy. Cardiomyocytes were sterile isola...

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Detalles Bibliográficos
Autores principales: Deng, Jianxin, Cai, Xiangsheng, Hao, Mingyu, Liu, Xueting, Chen, Zelong, Li, Haiyan, Liu, Junying, Liao, Yunxiu, Fu, Hao, Chen, Huiyan, Qin, Gangjian, Yan, Dewen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884338/
https://www.ncbi.nlm.nih.gov/pubmed/33604360
http://dx.doi.org/10.3389/fcvm.2021.637021