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Genome-wide analysis suggests the importance of vascular processes and neuroinflammation in late-life antidepressant response

Antidepressant outcomes in older adults with depression is poor, possibly because of comorbidities such as cerebrovascular disease. Therefore, we leveraged multiple genome-wide approaches to understand the genetic architecture of antidepressant response. Our sample included 307 older adults (≥60 yea...

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Detalles Bibliográficos
Autores principales: Marshe, Victoria S., Maciukiewicz, Malgorzata, Hauschild, Anne-Christin, Islam, Farhana, Qin, Li, Tiwari, Arun K., Sibille, Etienne, Blumberger, Daniel M., Karp, Jordan F., Flint, Alastair J., Turecki, Gustavo, Lam, Raymond W., Milev, Roumen V., Frey, Benicio N., Rotzinger, Susan, Foster, Jane A., Kennedy, Sidney H., Kennedy, James L., Mulsant, Benoit H., Reynolds, Charles F., Lenze, Eric J., Müller, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884410/
https://www.ncbi.nlm.nih.gov/pubmed/33589590
http://dx.doi.org/10.1038/s41398-021-01248-3