SChLAP1 promotes prostate cancer development through interacting with EZH2 to mediate promoter methylation modification of multiple miRNAs of chromosome 5 with a DNMT3a-feedback loop

This study aimed to investigate the mechanism of SChLAP1 (second chromosome locus associated with prostate-1) on microRNA expression in prostate cancer. Differential expression of lncRNAs and microRNA prostate cancer cells were predicted by informatics and confirmed by qRT-PCR. SChLAP1-interacting p...

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Detalles Bibliográficos
Autores principales: Huang, Kai, Tang, Yuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884413/
https://www.ncbi.nlm.nih.gov/pubmed/33589600
http://dx.doi.org/10.1038/s41419-021-03455-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884413/
https://www.ncbi.nlm.nih.gov/pubmed/33589600
http://dx.doi.org/10.1038/s41419-021-03455-8

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