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Structural design principles for specific ultra-high affinity interactions between colicins/pyocins and immunity proteins
The interactions of the antibiotic proteins colicins/pyocins with immunity proteins is a seminal model system for studying protein–protein interactions and specificity. Yet, a precise and quantitative determination of which structural elements and residues determine their binding affinity and specif...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884437/ https://www.ncbi.nlm.nih.gov/pubmed/33589691 http://dx.doi.org/10.1038/s41598-021-83265-2 |