Cargando…
Structural design principles for specific ultra-high affinity interactions between colicins/pyocins and immunity proteins
The interactions of the antibiotic proteins colicins/pyocins with immunity proteins is a seminal model system for studying protein–protein interactions and specificity. Yet, a precise and quantitative determination of which structural elements and residues determine their binding affinity and specif...
Autores principales: | Shushan, Avital, Kosloff, Mickey |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884437/ https://www.ncbi.nlm.nih.gov/pubmed/33589691 http://dx.doi.org/10.1038/s41598-021-83265-2 |
Ejemplares similares
-
Structural design principles that underlie the multi-specific interactions of Gα(q) with dissimilar partners
por: Navot, Shir, et al.
Publicado: (2019) -
Structures of the Ultra-High-Affinity Protein–Protein Complexes of Pyocins S2 and AP41 and Their Cognate Immunity Proteins from Pseudomonas aeruginosa
por: Joshi, Amar, et al.
Publicado: (2015) -
Structure and Function of Colicin S4, a Colicin with a Duplicated
Receptor-binding
Domain
por: Arnold, Thomas, et al.
Publicado: (2009) -
Plant-expressed pyocins for control of Pseudomonas aeruginosa
por: Paškevičius, Šarūnas, et al.
Publicado: (2017) -
Spatial structure maintains diversity of pyocin inhibition in household Pseudomonas aeruginosa
por: Mojesky, Aubrey A., et al.
Publicado: (2020)