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Inhibition of repulsive guidance molecule-a protects dopaminergic neurons in a mouse model of Parkinson’s disease
Repulsive guidance molecule-a (RGMa), a glycosylphosphatidylinositol-anchored membrane protein, has diverse functions in axon guidance, cell patterning, and cell survival. Inhibition of RGMa attenuates pathological dysfunction in animal models of central nervous system (CNS) diseases including spina...
Autores principales: | Oda, Wakana, Fujita, Yuki, Baba, Kousuke, Mochizuki, Hideki, Niwa, Hitoshi, Yamashita, Toshihide |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884441/ https://www.ncbi.nlm.nih.gov/pubmed/33589594 http://dx.doi.org/10.1038/s41419-021-03469-2 |
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