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Functionally Competent, PD-1(+) CD8(+) Trm Cells Populate the Brain Following Local Antigen Encounter
Expression of programmed cell death-1 receptor (PD-1) has traditionally been linked to T-cell exhaustion, as signaling via PD-1 dampens the functionality of T-cells upon repetitive antigen exposures during chronic infections. However, resent findings pointing to the involvement of PD-1 both in T-cel...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884456/ https://www.ncbi.nlm.nih.gov/pubmed/33603737 http://dx.doi.org/10.3389/fimmu.2020.595707 |