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Microglia induce neurogenic protein expression in primary cortical cells by stimulating PI3K/AKT intracellular signaling in vitro

Emerging evidence suggests that microglia can support neurogenesis. Little is known about the mechanisms by which microglia regulate the cortical environment and stimulate cortical neurogenesis. We used an in vitro co-culture model system to investigate the hypothesis that microglia respond to solub...

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Detalles Bibliográficos
Autores principales: Lorenzen, Kristi, Mathy, Nicholas W., Whiteford, Erin R., Eischeid, Alex, Chen, Jing, Behrens, Matthew, Chen, Xian-Ming, Shibata, Annemarie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884585/
https://www.ncbi.nlm.nih.gov/pubmed/33387198
http://dx.doi.org/10.1007/s11033-020-06092-0