Cargando…
Microglia induce neurogenic protein expression in primary cortical cells by stimulating PI3K/AKT intracellular signaling in vitro
Emerging evidence suggests that microglia can support neurogenesis. Little is known about the mechanisms by which microglia regulate the cortical environment and stimulate cortical neurogenesis. We used an in vitro co-culture model system to investigate the hypothesis that microglia respond to solub...
Autores principales: | Lorenzen, Kristi, Mathy, Nicholas W., Whiteford, Erin R., Eischeid, Alex, Chen, Jing, Behrens, Matthew, Chen, Xian-Ming, Shibata, Annemarie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884585/ https://www.ncbi.nlm.nih.gov/pubmed/33387198 http://dx.doi.org/10.1007/s11033-020-06092-0 |
Ejemplares similares
-
A novel long intergenic non-coding RNA, Nostrill, regulates iNOS gene transcription and neurotoxicity in microglia
por: Mathy, Nicholas W., et al.
Publicado: (2021) -
The Long Non-Coding RNA Nostrill Regulates Transcription of Irf7 Through Interaction With NF-κB p65 to Enhance Intestinal Epithelial Defense Against Cryptosporidium parvum
por: Mathy, Nicholas W., et al.
Publicado: (2022) -
Microglia from neurogenic and non-neurogenic regions display differential proliferative potential and neuroblast support
por: Marshall, Gregory P., et al.
Publicado: (2014) -
Getting the Akt Together: Guiding Intracellular Akt Activity by PI3K
por: Yudushkin, Ivan
Publicado: (2019) -
Exploring the role of microglia in cortical spreading depression in neurological disease
por: Shibata, Mamoru, et al.
Publicado: (2017)