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Pemafibrate prevents retinal neuronal cell death in NMDA-induced excitotoxicity via inhibition of p-c-Jun expression

Excitotoxicity is involved in the retinal neuronal cell death in diabetic retinopathy. Although fenofibrate has been shown to ameliorate the progression of diabetic retinopathy, the effect of pemafibrate, which is highly selective for peroxisome proliferator-activated receptor α on retinal neuronal...

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Detalles Bibliográficos
Autores principales: Fujita, Naoki, Sase, Kana, Tsukahara, Chihiro, Arizono, Ibuki, Takagi, Hitoshi, Kitaoka, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884588/
https://www.ncbi.nlm.nih.gov/pubmed/33278012
http://dx.doi.org/10.1007/s11033-020-06032-y