Single-Cell RNA Sequencing Reveals the Expansion of Cytotoxic CD4(+) T Lymphocytes and a Landscape of Immune Cells in Primary Sjögren’s Syndrome

OBJECTIVE: Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease, and its pathogenetic mechanism is far from being understood. In this study, we aimed to explore the cellular and molecular mechanisms that lead to pathogenesis of this disease. METHODS: We applied single-cell RNA sequencin...

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Detalles Bibliográficos
Autores principales: Hong, Xiaoping, Meng, Shuhui, Tang, Donge, Wang, Tingting, Ding, Liping, Yu, Haiyan, Li, Heng, Liu, Dongzhou, Dai, Yong, Yang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884617/
https://www.ncbi.nlm.nih.gov/pubmed/33603736
http://dx.doi.org/10.3389/fimmu.2020.594658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884617/
https://www.ncbi.nlm.nih.gov/pubmed/33603736
http://dx.doi.org/10.3389/fimmu.2020.594658

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