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Glycyrrhetinic Acid Protects Renal Tubular Cells against Oxidative Injury via Reciprocal Regulation of JNK-Connexin 43-Thioredoxin 1 Signaling

Background and Objective: The incidence of chronic kidney disease (CKD) is steadily increasing. Although renal tubular epithelium injury is closely correlated with the prognosis of CKD, the underlying mechanism is not fully understood and therapeutic strategies are limited. The main bioactive compon...

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Detalles Bibliográficos
Autores principales: Zhou, Yao, Gao, Leiping, Xia, Ping, Zhao, Jing, Li, Wei, Zhou, Yufeng, Wei, Qingxue, Wu, Qijing, Wu, Qi, Sun, Dongdong, Gao, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884636/
https://www.ncbi.nlm.nih.gov/pubmed/33603672
http://dx.doi.org/10.3389/fphar.2021.619567