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Caspase 3/GSDME-dependent pyroptosis contributes to chemotherapy drug-induced nephrotoxicity

Chemotherapy drug-induced nephrotoxicity limits clinical applications for treating cancers. Pyroptosis, a newly discovered programmed cell death, was recently reported to be associated with kidney diseases. However, the role of pyroptosis in chemotherapeutic drug-induced nephrotoxicity has not been...

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Detalles Bibliográficos
Autores principales: Shen, Xiujin, Wang, Haibing, Weng, Chunhua, Jiang, Hong, Chen, Jianghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884686/
https://www.ncbi.nlm.nih.gov/pubmed/33589596
http://dx.doi.org/10.1038/s41419-021-03458-5