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Exercise alters the mitochondrial proteostasis and induces the mitonuclear imbalance and UPR(mt) in the hypothalamus of mice

The maintenance of mitochondrial activity in hypothalamic neurons is determinant to the control of energy homeostasis in mammals. Disturbs in the mitochondrial proteostasis can trigger the mitonuclear imbalance and mitochondrial unfolded protein response (UPR(mt)) to guarantee the mitochondrial inte...

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Detalles Bibliográficos
Autores principales: Braga, Renata R., Crisol, Barbara M., Brícola, Rafael S., Sant’ana, Marcella R., Nakandakari, Susana C. B. R., Costa, Suleyma O., Prada, Patrícia O., da Silva, Adelino S. R., Moura, Leandro P., Pauli, José R., Cintra, Dennys E., Ropelle, Eduardo R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884690/
https://www.ncbi.nlm.nih.gov/pubmed/33589652
http://dx.doi.org/10.1038/s41598-021-82352-8