Cargando…
Exercise alters the mitochondrial proteostasis and induces the mitonuclear imbalance and UPR(mt) in the hypothalamus of mice
The maintenance of mitochondrial activity in hypothalamic neurons is determinant to the control of energy homeostasis in mammals. Disturbs in the mitochondrial proteostasis can trigger the mitonuclear imbalance and mitochondrial unfolded protein response (UPR(mt)) to guarantee the mitochondrial inte...
Autores principales: | Braga, Renata R., Crisol, Barbara M., Brícola, Rafael S., Sant’ana, Marcella R., Nakandakari, Susana C. B. R., Costa, Suleyma O., Prada, Patrícia O., da Silva, Adelino S. R., Moura, Leandro P., Pauli, José R., Cintra, Dennys E., Ropelle, Eduardo R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884690/ https://www.ncbi.nlm.nih.gov/pubmed/33589652 http://dx.doi.org/10.1038/s41598-021-82352-8 |
Ejemplares similares
-
Physical exercise elicits UPR(mt) in the skeletal muscle: The role of c-Jun N-terminal kinase
por: Gaspar, Rodrigo Stellzer, et al.
Publicado: (2023) -
Obesity Increases Mitogen-Activated Protein Kinase Phosphatase-3 Levels in the Hypothalamus of Mice
por: Rodrigues, Bárbara de A., et al.
Publicado: (2017) -
Temporal landscape of mitochondrial proteostasis governed by the UPR(mt)
por: Uoselis, Louise, et al.
Publicado: (2023) -
Mitonuclear protein imbalance as a conserved longevity mechanism
por: Houtkooper, Riekelt H., et al.
Publicado: (2013) -
UPR(mt) and coordinated UPR(ER) in type 2 diabetes
por: Kang, Zhanfang, et al.
Publicado: (2022)