TOM20-mediated transfer of Bcl2 from ER to MAM and mitochondria upon induction of apoptosis

In this work, we have explored the subcellular localization of Bcl2, a major antiapoptotic protein. In U251 glioma cells, we found that Bcl2 is localized mainly in the ER and is translocated to MAM and mitochondria upon induction of apoptosis; this mitochondrial transfer was not restricted to the de...

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Detalles Bibliográficos
Autores principales: Lalier, Lisenn, Mignard, Vincent, Joalland, Marie-Pierre, Lanoé, Didier, Cartron, Pierre-François, Manon, Stéphen, Vallette, François M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884705/
https://www.ncbi.nlm.nih.gov/pubmed/33589622
http://dx.doi.org/10.1038/s41419-021-03471-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884705/
https://www.ncbi.nlm.nih.gov/pubmed/33589622
http://dx.doi.org/10.1038/s41419-021-03471-8

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