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TOM20-mediated transfer of Bcl2 from ER to MAM and mitochondria upon induction of apoptosis
In this work, we have explored the subcellular localization of Bcl2, a major antiapoptotic protein. In U251 glioma cells, we found that Bcl2 is localized mainly in the ER and is translocated to MAM and mitochondria upon induction of apoptosis; this mitochondrial transfer was not restricted to the de...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884705/ https://www.ncbi.nlm.nih.gov/pubmed/33589622 http://dx.doi.org/10.1038/s41419-021-03471-8 |