Mapping drug-target interactions and synergy in multi-molecular therapeutics for pressure-overload cardiac hypertrophy

Advancements in systems biology have resulted in the development of network pharmacology, leading to a paradigm shift from “one-target, one-drug” to “target-network, multi-component therapeutics”. We employ a chimeric approach involving in-vivo assays, gene expression analysis, cheminformatics, and...

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Detalles Bibliográficos
Autores principales: Rai, Aparna, Kumar, Vikas, Jerath, Gaurav, Kartha, C. C., Ramakrishnan, Vibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884732/
https://www.ncbi.nlm.nih.gov/pubmed/33589646
http://dx.doi.org/10.1038/s41540-021-00171-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884732/
https://www.ncbi.nlm.nih.gov/pubmed/33589646
http://dx.doi.org/10.1038/s41540-021-00171-z

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