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cGAMP/Saponin Adjuvant Combination Improves Protective Response to Influenza Vaccination by Microneedle Patch in an Aged Mouse Model

Current strategies for improving protective response to influenza vaccines during immunosenescence do not adequately protect individuals over 65 years of age. Here, we used an aged mouse model to investigate the potential of co-delivery of influenza vaccine with the recently identified combination o...

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Detalles Bibliográficos
Autores principales: Vassilieva, Elena V., Li, Song, Korniychuk, Heorhiy, Taylor, Dahnide M., Wang, Shelly, Prausnitz, Mark R., Compans, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884748/
https://www.ncbi.nlm.nih.gov/pubmed/33603732
http://dx.doi.org/10.3389/fimmu.2020.583251