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The Therapeutic Targets of Fingolimod (FTY720) Are Involved in Pathological Processes in the Frontal Cortex of Alzheimer's Disease Patients: A Network Pharmacology Study

Background: The sphingosine-1-phosphate receptor (S1PR) modulator fingolimod (FTY720), which is commonly used as an immunomodulator in multiple sclerosis treatment, has recently been found to reduce pathological changes in the brain tissue of Alzheimer's disease (AD) animal models, but this has...

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Detalles Bibliográficos
Autores principales: Yin, Pengqi, Xue, Yang, Wang, Tingting, Zhong, Di, Li, Guozhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884771/
https://www.ncbi.nlm.nih.gov/pubmed/33603656
http://dx.doi.org/10.3389/fnagi.2021.609679