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Practical early cancer detection: distinguishing stable from unstable genomes in pre-cancerous tissues

Barrett’s oesophagus has been known for many years to display early changes to the genome consistent with the risk for oesophageal adenocarcinoma. Recently we have shown that this information can be used without knowledge of individual gene mutations to accurately predict a patient’s future risk of...

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Detalles Bibliográficos
Autores principales: Killcoyne, Sarah, Fitzgerald, Rebecca C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884797/
https://www.ncbi.nlm.nih.gov/pubmed/33154569
http://dx.doi.org/10.1038/s41416-020-01142-7