Causal network models of SARS-CoV-2 expression and aging to identify candidates for drug repurposing

Given the severity of the SARS-CoV-2 pandemic, a major challenge is to rapidly repurpose existing approved drugs for clinical interventions. While a number of data-driven and experimental approaches have been suggested in the context of drug repurposing, a platform that systematically integrates ava...

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Detalles Bibliográficos
Autores principales: Belyaeva, Anastasiya, Cammarata, Louis, Radhakrishnan, Adityanarayanan, Squires, Chandler, Yang, Karren Dai, Shivashankar, G. V., Uhler, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884845/
https://www.ncbi.nlm.nih.gov/pubmed/33589624
http://dx.doi.org/10.1038/s41467-021-21056-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884845/
https://www.ncbi.nlm.nih.gov/pubmed/33589624
http://dx.doi.org/10.1038/s41467-021-21056-z

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