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Apatinib Promotes Ferroptosis in Colorectal Cancer Cells by Targeting ELOVL6/ACSL4 Signaling

BACKGROUND: Colorectal cancer (CRC) is a common digestive system malignancy. Ferroptosis, a new form of regulated cell death, plays a vital role in the pathogenesis and therapy of cancers. OBJECTIVE: We aimed to study the role of apatinib in ferroptosis of CRC cells and its potential mechanisms. MAT...

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Detalles Bibliográficos
Autores principales: Tian, Xiangyang, Li, Shuyuan, Ge, Guoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884947/
https://www.ncbi.nlm.nih.gov/pubmed/33603479
http://dx.doi.org/10.2147/CMAR.S274631