Valproate Reverses Mania-Like Behavior of Clock(delta19) Mouse and Alters Monoamine Neurotransmitters Metabolism in the Hippocampus

BACKGROUND: Mice with a deletion at exon 19 of the circadian locomotor output cycles Kaput gene (Clock(delta19)) exhibit mania-like behavior and have been one of the most common animal models for bipolar disorder (BD). The predictive validity of the Clock(delta19) was investigated via studies using...

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Detalles Bibliográficos
Autores principales: Liu, Shasha, Wei, Jinxue, Ni, Rongjun, Gao, Tianhao, Ni, Peiyan, Zhao, Liansheng, Duan, Xiyu, Ma, Xiaohong, Sham, Pak C, Li, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884953/
https://www.ncbi.nlm.nih.gov/pubmed/33603383
http://dx.doi.org/10.2147/NDT.S293482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884953/
https://www.ncbi.nlm.nih.gov/pubmed/33603383
http://dx.doi.org/10.2147/NDT.S293482

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