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TGF-β1-Mediated Activation of SERPINE1 is Involved in Hemin-Induced Apoptotic and Inflammatory Injury in HT22 Cells

BACKGROUND: Intracerebral hemorrhage (ICH) is a severe subtype of stroke with high mortality and morbidity. Serpin Family E Member 1 (SERPINE1) has been documented to be upregulated following ICH, however, the participation of SERPINE1 in the development of ICH has never been studied. METHODS: Hemin...

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Detalles Bibliográficos
Autores principales: Wang, Tinggang, Lu, Haibin, Li, Deqiang, Huang, Weichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884960/
https://www.ncbi.nlm.nih.gov/pubmed/33603380
http://dx.doi.org/10.2147/NDT.S293772