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Association of β-Amyloid Level, Clinical Progression, and Longitudinal Cognitive Change in Normal Older Individuals

OBJECTIVE: To determine the effect of β-amyloid (Aβ) level on progression risk to mild cognitive impairment (MCI) or dementia and longitudinal cognitive change in cognitively normal (CN) older individuals. METHODS: All CN from the Australian Imaging Biomarkers and Lifestyle study with Aβ PET and ≥3...

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Detalles Bibliográficos
Autores principales: van der Kall, Laura M., Truong, Thanh, Burnham, Samantha C., Doré, Vincent, Mulligan, Rachel S., Bozinovski, Svetlana, Lamb, Fiona, Bourgeat, Pierrick, Fripp, Jurgen, Schultz, Stephanie, Lim, Yen Y., Laws, Simon M., Ames, David, Fowler, Christopher, Rainey-Smith, Stephanie R., Martins, Ralph N., Salvado, Olivier, Robertson, Joanne, Maruff, Paul, Masters, Colin L., Villemagne, Victor L., Rowe, Christopher C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884996/
https://www.ncbi.nlm.nih.gov/pubmed/33184233
http://dx.doi.org/10.1212/WNL.0000000000011222