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Poricoic acid A suppresses TGF-β1-induced renal fibrosis and proliferation via the PDGF-C, Smad3 and MAPK pathways

Renal interstitial fibrosis is the most important pathological process in chronic renal failure. Previous studies have shown that poricoic acid A (PAA), the main chemical constituent on the surface layer of the mushroom Poria cocos, has protective effects against oxidative stress and acute kidney in...

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Detalles Bibliográficos
Autores principales: Li, Qiang, Ming, Yao, Jia, Hu, Wang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885072/
https://www.ncbi.nlm.nih.gov/pubmed/33717232
http://dx.doi.org/10.3892/etm.2021.9720