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An Indispensable Role for the MavE Effector of Legionella pneumophila in Lysosomal Evasion

Diversion of the Legionella pneumophila-containing vacuole (LCV) from the host endosomal-lysosomal degradation pathway is one of the main virulence features essential for manifestation of Legionnaires’ pneumonia. Many of the ∼350 Dot/Icm-injected effectors identified in L. pneumophila have been show...

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Detalles Bibliográficos
Autores principales: Vaughn, Bethany, Voth, Kevin, Price, Christopher T., Jones, Snake, Ozanic, Mateja, Santic, Marina, Cygler, Miroslaw, Abu Kwaik, Yousef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885109/
https://www.ncbi.nlm.nih.gov/pubmed/33563829
http://dx.doi.org/10.1128/mBio.03458-20