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Partial Prion Cross-Seeding between Fungal and Mammalian Amyloid Signaling Motifs
In filamentous fungi, NLR-based signalosomes activate downstream membrane-targeting cell death-inducing proteins by a mechanism of amyloid templating. In the species Podospora anserina, two such signalosomes, NWD2/HET-S and FNT1/HELLF, have been described. An analogous system involving a distinct am...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885112/ https://www.ncbi.nlm.nih.gov/pubmed/33563842 http://dx.doi.org/10.1128/mBio.02782-20 |