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Partial Prion Cross-Seeding between Fungal and Mammalian Amyloid Signaling Motifs

In filamentous fungi, NLR-based signalosomes activate downstream membrane-targeting cell death-inducing proteins by a mechanism of amyloid templating. In the species Podospora anserina, two such signalosomes, NWD2/HET-S and FNT1/HELLF, have been described. An analogous system involving a distinct am...

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Detalles Bibliográficos
Autores principales: Bardin, Thierry, Daskalov, Asen, Barrouilhet, Sophie, Granger-Farbos, Alexandra, Salin, Bénédicte, Blancard, Corinne, Kauffmann, Brice, Saupe, Sven J., Coustou, Virginie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885112/
https://www.ncbi.nlm.nih.gov/pubmed/33563842
http://dx.doi.org/10.1128/mBio.02782-20