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Monoclonal Antibodies against Zika Virus NS1 Protein Confer Protection via Fcγ Receptor-Dependent and -Independent Pathways

Zika virus (ZIKV) infection during pregnancy causes congenital defects such as fetal microcephaly. Monoclonal antibodies (MAbs) against the nonstructural protein 1 (NS1) have the potential to suppress ZIKV pathogenicity without enhancement of disease, but the pathways through which they confer prote...

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Detalles Bibliográficos
Autores principales: Yu, Lei, Liu, Xinglong, Ye, Xianmiao, Su, Wan, Zhang, Xiaoyan, Deng, Weiqi, Luo, Jia, Xiang, Mengrong, Guo, Wenjing, Zhang, Shengnan, Xu, Wei, Yan, Qihong, Wang, Qian, Cui, Yilan, Wu, Caixia, Niu, Xuefeng, Zhang, Fuchun, Lei, Chunliang, Qu, Linbing, Chen, Ling, Feng, Liqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885117/
https://www.ncbi.nlm.nih.gov/pubmed/33563822
http://dx.doi.org/10.1128/mBio.03179-20