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Monoclonal Antibodies against Zika Virus NS1 Protein Confer Protection via Fcγ Receptor-Dependent and -Independent Pathways
Zika virus (ZIKV) infection during pregnancy causes congenital defects such as fetal microcephaly. Monoclonal antibodies (MAbs) against the nonstructural protein 1 (NS1) have the potential to suppress ZIKV pathogenicity without enhancement of disease, but the pathways through which they confer prote...
Autores principales: | Yu, Lei, Liu, Xinglong, Ye, Xianmiao, Su, Wan, Zhang, Xiaoyan, Deng, Weiqi, Luo, Jia, Xiang, Mengrong, Guo, Wenjing, Zhang, Shengnan, Xu, Wei, Yan, Qihong, Wang, Qian, Cui, Yilan, Wu, Caixia, Niu, Xuefeng, Zhang, Fuchun, Lei, Chunliang, Qu, Linbing, Chen, Ling, Feng, Liqiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885117/ https://www.ncbi.nlm.nih.gov/pubmed/33563822 http://dx.doi.org/10.1128/mBio.03179-20 |
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