Generation of a human Juvenile myelomonocytic leukemia iPSC line, CHOPi001-A, with a mutation in CBL

Juvenile myelomonocytic leukemia (JMML) is a rare myeloproliferative disorder of early childhood characterized by expansion of clonal myelomonocytic cells and hyperactive Ras/MAPK signaling. The disorder is caused by somatic and/or germline mutations in genes involved in the Ras/MAPK and JAK/STAT si...

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Detalles Bibliográficos
Autores principales: Gagne, Alyssa L., Maguire, Jean Ann, Gandre-Babbe, Shilpa, Chou, Stella T., Tasian, Sarah K., Loh, Mignon L., Weiss, Mitchell J., Gadue, Paul, French, Deborah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885123/
https://www.ncbi.nlm.nih.gov/pubmed/30096712
http://dx.doi.org/10.1016/j.scr.2018.07.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885123/
https://www.ncbi.nlm.nih.gov/pubmed/30096712
http://dx.doi.org/10.1016/j.scr.2018.07.001

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