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Beyond adverse outcome pathways: making toxicity predictions from event networks, SAR models, data and knowledge

Adverse outcome pathways have shown themselves to be useful ways of understanding and expressing knowledge about sequences of events that lead to adverse outcomes (AOs) such as toxicity. In this paper we use the building blocks of adverse outcome pathways—namely key events (KEs) and key event relati...

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Detalles Bibliográficos
Autores principales: Ball, Thomas, Barber, Christopher G, Cayley, Alex, Chilton, Martyn L, Foster, Robert, Fowkes, Adrian, Heghes, Crina, Hill, Emma, Hill, Natasha, Kane, Steven, Macmillan, Donna S, Myden, Alun, Newman, Daniel, Polit, Artur, Stalford, Susanne A, Vessey, Jonathan D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885198/
https://www.ncbi.nlm.nih.gov/pubmed/33613978
http://dx.doi.org/10.1093/toxres/tfaa099