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Hemozoin Promotes Lung Inflammation via Host Epithelial Activation

Respiratory distress in severe malaria is associated with high mortality, but its pathogenesis remains unclear. The malaria pigment hemozoin (HZ) is abundant in target organs of severe malaria, including the lungs, and is known to be a potent innate immune activator of phagocytes. We hypothesized th...

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Detalles Bibliográficos
Autores principales: Shah, Shivang S., Fidock, David A., Prince, Alice S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885402/
https://www.ncbi.nlm.nih.gov/pubmed/33563839
http://dx.doi.org/10.1128/mBio.02399-20