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Hemozoin Promotes Lung Inflammation via Host Epithelial Activation
Respiratory distress in severe malaria is associated with high mortality, but its pathogenesis remains unclear. The malaria pigment hemozoin (HZ) is abundant in target organs of severe malaria, including the lungs, and is known to be a potent innate immune activator of phagocytes. We hypothesized th...
Autores principales: | Shah, Shivang S., Fidock, David A., Prince, Alice S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885402/ https://www.ncbi.nlm.nih.gov/pubmed/33563839 http://dx.doi.org/10.1128/mBio.02399-20 |
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