Development of a new barcode-based, multiplex-PCR, next-generation-sequencing assay and data processing and analytical pipeline for multiplicity of infection detection of Plasmodium falciparum

BACKGROUND: Simultaneous infection with multiple malaria parasite strains is common in high transmission areas. Quantifying the number of strains per host, or the multiplicity of infection (MOI), provides additional parasite indices for assessing transmission levels but it is challenging to measure...

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Detalles Bibliográficos
Autores principales: Mitchell, Rebecca M., Zhou, Zhiyong, Sheth, Mili, Sergent, Sheila, Frace, Michael, Nayak, Vishal, Hu, Bin, Gimnig, John, ter Kuile, Feiko, Lindblade, Kim, Slutsker, Laurence, Hamel, Mary J., Desai, Meghna, Otieno, Kephas, Kariuki, Simon, Vigfusson, Ymir, Shi, Ya Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885407/
https://www.ncbi.nlm.nih.gov/pubmed/33593329
http://dx.doi.org/10.1186/s12936-021-03624-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885407/
https://www.ncbi.nlm.nih.gov/pubmed/33593329
http://dx.doi.org/10.1186/s12936-021-03624-2

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