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WACS: improving ChIP-seq peak calling by optimally weighting controls

BACKGROUND: Chromatin immunoprecipitation followed by high throughput sequencing (ChIP-seq), initially introduced more than a decade ago, is widely used by the scientific community to detect protein/DNA binding and histone modifications across the genome. Every experiment is prone to noise and bias,...

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Detalles Bibliográficos
Autores principales: Awdeh, Aseel, Turcotte, Marcel, Perkins, Theodore J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885521/
https://www.ncbi.nlm.nih.gov/pubmed/33588754
http://dx.doi.org/10.1186/s12859-020-03927-2